Nonunion of the humeral shaft successfully treated with teriparatide [rh (1-34) PTH]
نویسندگان
چکیده
We reported a case of atrophic nonunion after humeral shaft fracture in a patient with severe psychiatric disorders that advised against hospital admission and surgery. He was treated with teriparatide (recombinant human 1-34 parathyroid hormon) [rh (1-34) PTH] in daily subcutaneous injections. After 4 months of treatment, healing of nonunion, associated to clinical improvement and functional recovery of the patient, was observed. No other intervention was required, and no side effects attributable to the drug occurred.
منابع مشابه
Ilizarov treatment of humeral shaft nonunion in an antiepileptic drug patient with uncontrolled generalized tonic-clonic seizure activity
Nonunion of the humeral shaft in patients with antiepileptic drug associated metabolic bone disorder constitute a challenging surgical problem difficult to treat due to seizure activity, osteoporosis, and poor stabilization options. We report a case of nonunion of the humeral shaft in an antiepileptic drug patient with uncontrolled generalized tonic-clonic seizure activity successfully treated ...
متن کاملSuccessful Bone Healing of Nonunion After Ulnar Shortening Osteotomy for Smokers Treated With Teriparatide.
Ulnar shortening osteotomy is widely performed as the standard surgical treatment for ulnar impaction syndrome and has a high percentage of success for pain relief. However, delayed union and nonunion of the osteotomy site remain the most concerning complications. In particular, smokers have a higher incidence of nonunion, which amounts to 30% of cases. For the treatment of nonunion, secondary ...
متن کاملPTH 1-34 (teriparatide) may not improve healing in proximal humerus fractures
BACKGROUND AND PURPOSE There is solid evidence from animal experiments that parathyroid hormone (PTH) improves fracture healing. So far, only 3 papers on PTH and fracture repair in humans have been published. They suggest that PTH may enhance fracture healing, but the results do not appear to justify specific clinical recommendations. This study was carried out to determine whether teriparatide...
متن کاملنتایج درمان شکستگی تنه هومروس به روش میلهگذاری اینترمدولاری
Background & Aim: Most acute humeral shaft fractures can be successfully treated by conservative methods. Operation is recommended for certain fractures. Intramedullary nailing offers a dependable solution for the treatment of humeral shaft fractures, especially in polytrauma patients. The aim of this study was to evaluate intramedullary nailing outcomes and complications in humeral fractur...
متن کاملCase-Match Controlled Comparison of Minimally Invasive Plate Osteosynthesis and Intramedullary Nailing for the Stabilization of Humeral Shaft Fractures.
OBJECTIVES To compare the risk of major complications after either minimally invasive plate osteosynthesis (MIPO) or intramedullary nailing (IMN) of humeral shaft fractures. DESIGN Retrospective, case-match controlled study. SETTING A major metropolitan tertiary referral trauma center in Australia. PATIENTS Thirty patients with fractures of the humeral shaft. INTERVENTION Either MIPO or...
متن کامل